Shikonin - chinthu chatsopano chachilengedwe cha antibacterial chomwe chimayambitsa kusintha kwa ma antibiotic

Shikonin- chinthu chatsopano chachilengedwe cha antibacterial chomwe chimayambitsa kusintha kwa ma antibiotic

Posachedwapa, asayansi apeza chinthu chatsopano cha antibacterial, shikonin, mu chuma cha zomera. Kutulukira kumeneku kwadzutsa chidwi ndi chisangalalo padziko lonse lapansi. Shikonin ali ndi ntchito yolimbana ndi mabakiteriya ambiri ndipo akuyembekezeka kukhala wofunikira kwambiri pakupanga maantibayotiki atsopano. Shikonin amachokera ku chomera chotchedwa comfrey, chomwe chimamera kumadera a Asia, Europe, ndi North America. Shikonin ali ndi utoto wofiirira ndipo amagwiritsidwa ntchito kwambiri popanga utoto ndi mankhwala azitsamba. Komabe, kafukufuku waposachedwa akuwonetsa kuti shikonin sizokongola kokha, komanso ndi antibacterial wothandizira.

Poyesera, asayansi adapeza kuti shikonin ili ndi mphamvu yoletsa mabakiteriya osiyanasiyana ndi bowa. Sizokhazo, imathanso kukhala ndi mphamvu yowononga mabakiteriya ena osamva mankhwala, zomwe ndizofunikira kwambiri pavuto lalikulu lomwe lilipo la kukana maantibayotiki. Ofufuzawo adapezanso kuti shikonin imatha kugwiritsa ntchito antibacterial effect powononga nembanemba ya cell ya bakiteriya ndikuletsa kukula kwake. Njirayi ndi yosiyana ndi mankhwala omwe alipo kale, omwe amapereka njira yatsopano yopangira maantibayotiki. Pofuna kutsimikiziranso kuti shikonin ndi yothandiza komanso yotetezeka, ofufuzawo adachita zoyeserera zingapo mu vivo ndi mu vitro.

Chosangalatsa ndichakuti shikonin adawonetsa ntchito yabwino yachilengedwe popanda kuyambitsa zovuta zoyipa. Izi zimapangitsa shikonin kukhala antibacterial wothandizira ndipo imalowetsa mphamvu zatsopano mu kafukufuku ndi chitukuko cha maantibayotiki. Ngakhale kuti kupezeka kwa shikonin kwabweretsa chiyembekezo, asayansi amakumbutsanso anthu kuti chitukuko ndi kugwiritsa ntchito mankhwala oletsa tizilombo toyambitsa matenda ayenera kukhala osamala. Kugwiritsiridwa ntchito molakwa ndi kugwiritsiridwa ntchito mopambanitsa kwa mankhwala ophera majeremusi kwadzetsa vuto la padziko lonse la kukana mankhwala, chotero maantibayotiki atsopano ayenera kugwiritsiridwa ntchito ndi kusamaliridwa mwanzeru.

Kuonjezera apo, asayansi adapemphanso kuti amalonda ndi boma awonjezere ndalama ndi kuthandizira kufufuza ndi chitukuko cha antimicrobial pofuna kulimbikitsa chitukuko cha mankhwala atsopano. Pakadali pano, kafukufuku wa shikonin wakopa chidwi padziko lonse lapansi. Makampani angapo opanga mankhwala ndi mabungwe ofufuza akuwonjezera kafukufuku ndi chitukuko cha ma antibacterial agents okhudzana ndi shikonin.

Ofufuzawo adanena kuti apitiliza kuphunzira momwe ma cell a shikonin amagwirira ntchito kuti afufuze bwino zomwe angathe. Ndi kupita patsogolo kosalekeza kwa mankhwala ophera mabakiteriya, kupezeka kwa shikonin kwadzetsa chilimbikitso chatsopano mu kusintha kwa ma antibiotic. Zimapereka chiyembekezo ndikuyala maziko a mbadwo watsopano wa mankhwala opha tizilombo. Titha kuwona kuti kafukufuku wa shikonin adzalimbikitsa zatsopano pazamankhwala ndikubweretsa zisankho zambiri ndi ziyembekezo ku thanzi laumunthu.